|  Volumen:    20     # Number : 2 Publication Date :    Mayo - Agosto    Year:    2016
 ALK-positive diffuse large B-cell lymphoma:
a diagnostic and therapeutic challenge Authors: Degiorgi, C; Capitani, R; Lupo, N; Chiquini, Y;
Mosso, M; Martínez Bernal, M; Labanca, V Abstract: Diffuse large B cell lymphoma (DLBCL) is now
considered a clinical-pathological entity.
The DLBCL ALK positive (+) is a rare (<1%) and
distinct histologic variant with plasma cell differentiation,
own clinical, histopathological and immunohistochemical
characteristics, usually aggressive
clinical behavior, poor prognosis and bad response
to currently available therapies. Key words: ALK,
DLBCL,
WHO classification Pages :  |