Volumen: 18 # Number : 2
Publication Date : Mayo - Agosto Year: 2014
PEDIATRÍA ARTÍCULO ORIGINAL |
Acute pancreatitis by L Asparaginase
in a pediatric patient with
Acute Lymphoblastic leukemia
Authors: Wittmund, Laureana; Ferrero, Alexis; Castro Huergo, María; Morán, Lorena; Aversa Luis.
Abstract: Acute Lymphoblastic Leukemia (ALL) is the most frequent
malignant disease in childhood. With current treatment,global event free survival (EFS) over 80 % can be achieved. Treatment is based on combined chemotherapy
and it is associated to multiple adverse effects. We discuss a 4 year old girl who presents L-asparginase associated
acute necrotizing pancreatitis as asevere adverse effect during Induction phase, which evolves to the formation
of a pseudocyst.
A review on pharmacological properties of this drug and its complications is also presented.
Key words: Pancreatitis,
L Asparaginase
Acute Lymphoblastic Leukemia
Pages : 159-163
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