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Revista Argentina de Hematología

Abstract

Volumen:    22    # Number : 2

Publication Date :    Mayo - Agosto    Year:    2018

   ARTÍCULO ORIGINAL

Distribution of JAK2, MPL and CALR mutations in patients with suspected Phi negative myeloproliferative neoplasms from Buenos Aires public hospitals

Authors: Sieza Y, Di Camilo I, Mazziotta L, Archuby ML, Riva ME, Orellano L.

Abstract: Chronic myeloproliferative neoplasms (MPN) are clonal disorders of hematopoiesis with proliferation of one or more myeloid lines. Policytemia vera (PV), essential thrombocytemia (ET) and primary myelofibrosis (PMF) are usually referred to as “classical” (cMPN). Mutations in JAK2, MPL and CALR are the main molecular markers of cMPN and they are part of the diagnostic criteria.

Key words: cMPN, mutations, JAK2, CALR, MPL.

Pages : 151-156

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