Sociedad Argentina de Hematología

ISSN 2250-8309

FORMULARIOS

Declaración de Conflictos de Interés

Cesión de Derechos de Autor


Se solicita enviar ambos formularios a: revista@sah.org.ar

 

 

 

Revista Argentina de Hematología

Abstract

Volumen:    21    # Number : 2

Publication Date :    Mayo - Agosto    Year:    2017

   CASO CLÍNICO

Trans retinoic acid-induced myositis

Authors: Ghelfi A, Vismara V, Buffoni M, Parody R, Más Y, Ferreiro M, Fresco A, Street E, Rossi H

Abstract: Drug-induced myopathy is common in clinical practice. However, the development of severe myositis by agents such as all-trans retinoic acid (ATRA) is not usual, with only a few cases reported in the literature. ATRA is currently the standard therapy for the treatment of acute promyelocytic leukemia and is generally well tolerated, with exceptional development of myositis caused by ATRA, with isolated presentation and without association with Sweet’s syndrome. The clinical manifestations are variable, as well as the analytical behavior of muscle enzymes. It is characteristic the resolution of symptoms by the withdrawal of the drug and the use of high doses of steroids. Its early recognition is essential; since only the prompt withdrawal of the causal agent can lead to resolution. We report a case of myositis induced by ATRA.

Key words: Myositis, Drug induced, Trans retinoic acid, Promyelocytic leukemia.

Pages :

  Resumen             pdf  

SOCIEDAD ARGENTINA DE HEMATOLOGÍA
Julián Alvarez 146 - Ciudad Autónoma de Bs As - Argentina
(54-11) 4855-2452 / 2485

http://www.sah.org.ar/revista/